SS-31 Research Peptide — 99.5% Purity, Third-Party COA Verified | Peptide.co
Certificate of Analysis (COA) for SS-31 — Third-Party HPLC Purity Verification | Peptide.co
Certificate of Analysis (COA) for SS-31 — Third-Party HPLC Purity Verification | Peptide.co

SS-31

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Every batch is third-party tested by independent U.S. laboratories. We guarantee 99%+ purity on all research peptides with full COA documentation available for every product.

Dispatches within 24 hours of ordering! We source and ship from united states. Shipping usually takes 2-5 business days

All peptides are manufactured in FDA-registered facilities, then tested and shipped from the United States. We maintain strict quality control standards and follow current Good Manufacturing Practices (cGMP).

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All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. peptide co does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

What is SS-31?

SS-31, also known as Elamipretide, is a tetrapeptide that selectively targets the inner mitochondrial membrane. It is studied for its role in preserving mitochondrial function, reducing oxidative stress, and enhancing ATP production. Researchers investigate its potential therapeutic applications in a variety of age-related and metabolic disorders. This high-purity, lyophilized (powdered) peptide is manufactured for in vitro studies and controlled laboratory analysis only. Each vial undergoes rigorous quality control to ensure consistency in research applications.
Key Details
Chemical Formula
C32H49N9O5
Molecular Mass
639.78 Da
CAS Number
736992-21-5
Vial Size
10mg-50mg
Vial Contents
Elamipretide (10mg-50mg)

Frequently Asked Questions

What is SS-31?
+

SS-31 is a 4-amino acid research peptide. CAS Number: 736992-21-5. Molecular weight: 639.8 Da.

What has SS-31 been studied for in research?
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Mitochondrial dysfunction in kidney disease (Oxidative Medicine and Cellular Longevity, 2022[ neuroinflammation and synaptic impairment (Journal of Neuroinflammation, 2019[ pulmonary fibrosis (Antioxidants, 2023[ aging skeletal muscle and heart (Geroscience, 2023[ spinal cord injury (IJMS, 2025[ All findings referenced are from preclinical and in vitro studies. No approved clinical applications exist for this research compound.

How should SS-31 be stored for research use?
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-20°C or below in desiccated/sealed container, protected from light; stable for years when lyophilized Avoid repeated freeze-thaw cycles. Once reconstituted, the solution should be refrigerated at 2-8°C and used within 28 days.

What is the purity of Peptide.co's SS-31?
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Every batch of SS-31 from Peptide.co undergoes independent third-party HPLC testing. Current verified batches: 10mg batch (Lot #YPB.245): 99.1% purity; 50mg batch (Lot #YPB.246): 99.3% purity. Full Certificates of Analysis are publicly available at coa.peptide.co, covering HPLC purity, mass spectrometry identity confirmation, heavy metals screening (<20 ppb), and microbial limits (TAMC/TYMC: 0 CFU). All products are manufactured in FDA-registered facilities in the United States.

What is the mechanism of action of SS-31 in research models?
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Selectively binds cardiolipin (CL) in inner mitochondrial membrane (IMM), stabilizes mitochondrial cristae structure, improves electron transport chain efficiency and ATP production, reduces reactive oxygen species (ROS), interacts with IMM proteins like ANT to enhance ADP/ATP exchange (PNAS 2020[ IJMS 2025[ These mechanisms have been characterized in preclinical models only.

How is SS-31 reconstituted for laboratory use?
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SS-31 is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before use in research applications. The standard reconstitution solvent is bacteriostatic water (sterile water containing 0.9% benzyl alcohol). When reconstituting, direct the solvent gently along the inside wall of the vial — do not spray directly onto the lyophilized powder. Allow the peptide to dissolve naturally without shaking or vortexing. For detailed reconstitution volume calculations, use the free Bacteriostatic Water Calculator or Peptide Reconstitution Calculator on Peptide.co.

All products are for research use only. Not for human consumption. These statements have not been evaluated by the FDA.

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Certificate of Analysis

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Certificate of Analysis (COA) for SS-31 — Third-Party HPLC Purity Verification | Peptide.co
Certificate of Analysis (COA) for SS-31 — Third-Party HPLC Purity Verification | Peptide.co

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All products on this website are to be used strictly only for research purposes.
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