Selank is a 7-amino acid research peptide. CAS Number: 129954-34-3. Molecular weight: 751.9 Da.

Stress response and gene expression in hippocampus and spleen (Neurochem Res, 2024 link.springer.com/10.1134/S2635167624601335); ethanol-induced memory impairment via BDNF regulation (Bull Exp Biol Med, 2019 link.springer.com/10.1007/s10517-019-04588-9); morphine withdrawal signs (Bull Exp Biol Med, 2022 link.springer.com/10. All findings referenced are from preclinical and in vitro studies. No approved clinical applications exist for this research compound.

Store lyophilized powder at -20°C or preferably -80°C in a tightly sealed container, protected from light and moisture (Sigma-Aldrich). Avoid repeated freeze-thaw cycles. Once reconstituted, the solution should be refrigerated at 2-8°C and used within 28 days.

Peptide.co’s Selank has been verified at 99.5% purity through independent third-party HPLC testing. The current batch (Lot #YPB.228, 10mg) includes a full Certificate of Analysis confirming identity, purity, and peptide content. All COAs are publicly available at coa.peptide.co. Testing covers HPLC purity analysis, mass spectrometry identity confirmation, heavy metals screening (<20 ppb), and microbial limits (TAMC/TYMC: 0 CFU). All products are manufactured in FDA-registered facilities in the United States.

Positive allosteric modulation of GABA receptors (Curr Med Chem, 2018 pubmed.ncbi.nlm.nih.gov/30255741/); modulation of monoamine neurotransmitters, BDNF elevation in hippocampus, inhibition of enkephalin-degrading enzymes; influence on IL-6 and T helper cytokines (Wikipedia en.wikipedia.org/wiki/Selank). These mechanisms have been characterized in preclinical models only.

Selank is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before use in research applications. The standard reconstitution solvent is bacteriostatic water (sterile water containing 0.9% benzyl alcohol). When reconstituting, direct the solvent gently along the inside wall of the vial — do not spray directly onto the lyophilized powder. Allow the peptide to dissolve naturally without shaking or vortexing. For detailed reconstitution volume calculations, use the free Bacteriostatic Water Calculator or Peptide Reconstitution Calculator on Peptide.co.