CJC-1295 With DAC is a 30-amino acid synthetic GHRH analog conjugated with a Drug Affinity Complex (DAC) that extends its biological half-life by binding to serum albumin. CAS Number: 863288-34-0. Molecular weight: approximately 3647.3 Da. The DAC modification allows for sustained activity in preclinical research models compared to non-DAC variants.

Preclinical studies on GH/IGF-1 axis activation, prolonged GH secretion, pituitary receptor binding via bioconjugation, pulsatile GH release, and doping detection in equine plasma (Endocrinology 2005; JCEM 2006; Drug Test Anal 2019) All findings referenced are from preclinical and in vitro studies. No approved clinical applications exist for this research compound.

-20°C or below (preferably -80°C) in sealed container, protected from light/moisture Avoid repeated freeze-thaw cycles. Once reconstituted, the solution should be refrigerated at 2-8°C and used within 28 days.

Peptide.co’s CJC-1295 With DAC has been verified at 99.5% purity through independent third-party HPLC testing. The current batch (Lot #YPB.220, 5mg) includes a full Certificate of Analysis confirming identity, purity, and peptide content. All COAs are publicly available at coa.peptide.co. Testing covers HPLC purity analysis, mass spectrometry identity confirmation, heavy metals screening (<20 ppb), and microbial limits (TAMC/TYMC: 0 CFU). All products are manufactured in FDA-registered facilities in the United States.

GHRH analog that covalently binds plasma albumin via maleimide-DAC moiety, extending half-life; activates pituitary GHRH receptors to stimulate cAMP-mediated GH release while preserving pulsatility These mechanisms have been characterized in preclinical models only.

CJC-1295 With DAC is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before use in research applications. The standard reconstitution solvent is bacteriostatic water (sterile water containing 0.9% benzyl alcohol). When reconstituting, direct the solvent gently along the inside wall of the vial — do not spray directly onto the lyophilized powder. Allow the peptide to dissolve naturally without shaking or vortexing. For detailed reconstitution volume calculations, use the free Bacteriostatic Water Calculator or Peptide Reconstitution Calculator on Peptide.co.