BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids (sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val). It is derived from a partial sequence of a protective protein found in human gastric juice. BPC-157 has a molecular weight of 1419.5 Da and a CAS number of 137525-51-0. It was first described in research literature in 1993 and has since been the subject of numerous preclinical studies investigating its cytoprotective and regenerative properties.

In preclinical animal models, BPC-157 has been investigated for its effects on tissue repair across multiple systems. Published studies have examined its role in tendon, ligament, muscle, and bone healing in rodent models. Research has also explored its interaction with the VEGF (vascular endothelial growth factor) pathway, nitric oxide system, and growth factor signaling (ERK1/2, EGR-1). A 2025 systematic review in HSS Journal noted that BPC-157 demonstrated cytoprotective effects across a range of organs and tissues in preclinical settings. All findings are based on in vitro and animal studies — no approved clinical applications exist.

Lyophilized (freeze-dried) BPC-157 should be stored at -20°C or below for long-term stability. Under these conditions, peptides in powder form can remain stable for one to several years. For short-term storage (weeks to a few months), refrigeration at 2-8°C is acceptable. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2-8°C and used within 28 days. Avoid repeated freeze-thaw cycles, exposure to light, and contamination by using sterile technique during handling.

BPC-157 is independently tested by Analytical Formulations, Inc., a cGLP-certified third-party laboratory. The 5mg vial (Lot YPB.212) tested at 99.5% purity, and the 10mg vial (Lot YPB.213) tested at 99.9% purity, both verified via UV/Vis Spectrophotometry on January 14, 2026. Additional testing confirmed heavy metals below 20ppb (limit: 150ppb/vial), 0 CFU on microbial counts, and quantitative assay within label claim. Full Certificates of Analysis for every batch are publicly available at coa.peptide.co.

BPC-157 is available in two common forms: the free base (CAS 137525-51-0) and the acetate salt (CAS 216441-37-1). The free base is the peptide in its unmodified form, while the acetate salt includes an acetate counterion from the purification process. The acetate salt form has a slightly higher molecular weight (1478.7 Da vs. 1419.5 Da) due to the attached acetate group. Both forms contain the same active 15-amino-acid peptide sequence. The acetate form is more commonly available as it is the typical result of standard HPLC purification.

BPC-157 is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before use in research applications. The standard reconstitution solvent is bacteriostatic water (sterile water containing 0.9% benzyl alcohol). When reconstituting, direct the solvent gently along the inside wall of the vial — do not spray directly onto the lyophilized powder. Allow the compound to dissolve naturally without shaking or vortexing. For detailed reconstitution volume calculations, use our free Peptide Reconstitution Calculator or Bacteriostatic Water Calculator.